Publications
Adler O, Zait Y, Cohen N, Blazquez R, Doron H, Monteran L, Scharff Y, Shami T, Mundhe D, Glehr G, Kanner A A, Horn S, Yahalom V, Haferkamp S, Hutchinson J A, Bleckmann A, Nahary L, Benhar I, Yust Katz S, Pukrop T, and Erez N. (2023). Reciprocal interactions between innate immune cells and astrocytes facilitate neuroinflammation and brain metastasis via lipocalin-2. Nature Cancer 4: 401-418. doi: 10.1038/s43018-023-00519-w
Agudo, J., Aguirre-Ghiso, J.A., Bhatia, M., Chodosh, L.A., Correia, A.L. & Klein, C.A.. Targeting cancer cell dormancy. Nat Rev Cancer 24, 97–104 (2024). https://doi.org/10.1038/s41568-023-00642-x
Amon L, Dudziak D, Backer RA, Clausen BE, Gmeiner C, Heger L, Jacobi L, Lehmann CHK, Probst HC, Seichter A, Tchitashvili G, Tochoedo NR, Trapaidze L, Vurnek D. 2022. Guidelines for DC preparation and flow cytometry analysis of mouse lymphohematopoietic tissues. Eur J Immunol n/a. https://doi.org/10.1002/eji.202249893
Angeloni M, Rizzi D, Schoen S, Caputo A, Merolla F, Hartmann A, Ferrazzi F*, Fraggetta F*. Closing the gap in the clinical adoption of computational pathology: a standardized, open-source framework to integrate deep-learning algorithms into the laboratory information system. bioRxiv 2024.07.11.603091; doi: https://doi.org/10.1101/2024.07.11.603091 (*: shared last authorship)
Angeloni M, van Doeveren T, Lindner S, Volland P, Schmelmer J, Foersch S, Matek C, Stoehr R, Geppert CI, Heers H, Wach S, Taubert H, Sikic D, Wullich B, van Leenders GJ, Zaburdaev V, Eckstein M, Hartmann A, Boormans JL, Ferrazzi F*, Bahlinger V*. A deep-learning workflow to predict upper tract urothelial carcinoma protein-based subtypes from H&E slides supporting the prioritization of patients for molecular testing. J Pathol Clin Res. 2024 Mar;10(2):e12369. doi: 10.1002/2056-4538.12369. (*: shared last authorship)
Baasch, S., Giansanti, P., Kolter, J., Riedl, A., Forde, A. J., Runge, S., Zenke, S., Elling, R., Halenius, A., Brabletz, S., Hengel, H., Kuster, B., Brabletz, T., Cicin-Sain, L., Arens, R., Vlachos, A., Rohr, J. C., Stemmler, M. P., Kopf, M., Ruzsics, Z., … Henneke, P. (2021). Cytomegalovirus subverts macrophage identity. Cell, 184(14), 3774–3793.e25. https://doi.org/10.1016/j.cell.2021.05.009
Bäuerle, T., Gupta, S., Zheng, S., Seyler, L., Leporati, A., Marosfoi, M., Maschauer, S., Prante, O., Caravan, P., & Bogdanov, A., Jr (2021). Multimodal Bone Metastasis-associated Epidermal Growth Factor Receptor Imaging in an Orthotopic Rat Model. Radiology. Imaging cancer, 3(4), e200069. https://doi.org/10.1148/rycan.2021200069
Bénard A, Mittelstädt A, Klösch B, Glanz K, Müller J, Schoen J, Nüse B, Brunner M, Naschberger E, Stürzl M, Mattner J, Muñoz LE, Sohn K, Grützmann R, Weber GF. IL-3 orchestrates ulcerative colitis pathogenesis by controlling the development and the recruitment of splenic reservoir neutrophils. Cell Rep. 2023 Jun 8;42(6):112637. doi: 10.1016/j.celrep.2023.112637
Bittner S, Hehlgans T, and Feuerer M. (2023). Engineered Treg cells as putative therapeutics against inflammatory diseases and beyond. Trends Immunol 44: 468-483. doi: 10.1016/j.it.2023.04.005
Blazquez R, Chuang H-N, Wenske B, Trigueros L, Wlochowitz D, Liguori R, Ferrazzi F, Regen T, Proescholdt M A, Rohde V, Riemenschneider M J, Stadelmann C, Bleckmann A, Beißbarth T, van Rossum D, Hanisch U K, and Pukrop T (2022a). Intralesional TLR4 agonist treatment strengthens the organ defense against colonizing cancer cells in the brain. Oncogene 41: 5008-5019. doi: 10.1038/s41388-022-02496-3
Blazquez R, Proescholdt M A, Klauser M, Schebesch K-M, Doenitz C, Heudobler D, Stange L, Riemenschneider M J, Bumes E, Rosengarth K, Schicho A, Schmidt N-O, Brawanski A, Pukrop T, and Wendl C. (2022b). Breakouts—A Radiological Sign of Poor Prognosis in Patients With Brain Metastases. Frontiers in Oncology 12. doi: 10.3389/fonc.2022.849880
Blazquez R, Sparrer D, Sonbol J, Philipp J, Schmieder F, and Pukrop T (2024). Organotypic 3D Ex Vivo Co-culture Model of the Macro-metastasis/Organ Parenchyma Interface. In 3D Cell Culture: Methods and Protocols, Z. Sumbalova Koledova, ed. (New York, NY: Springer US), pp. 165-176. doi: 10.1007/978-1-0716-3674-9_12
Brabletz, S., Schuhwerk, H., Brabletz, T., & Stemmler, M. P. (2021). Dynamic EMT: a multi-tool for tumor progression. The EMBO journal, 40(18), e108647. https://doi.org/10.15252/embj.2021108647
Busenhart, P., Montalban-Arques, A., Katkeviciute, E., Morsy, Y., Van Passen, C., Hering, L., Atrott, K., Lang, S., Garzon, J., Naschberger, E., Hartmann, A., Rogler, G., Stürzl, M., Spalinger, M. R., & Scharl, M. (2022). Inhibition of integrin αvβ6 sparks T-cell antitumor response and enhances immune checkpoint blockade therapy in colorectal cancer. Journal for immunotherapy of cancer, 10(2), e003465. https://doi.org/10.1136/jitc-2021-003465
Carta MG, Toegel L, Hoelsken A, Schubart C, Sticht H, Stoehr R, Spoerl S, Meidenbauer N, Hartmann A, Magni P, Haller F, Ferrazzi F. medRxiv 2024.10.10.24315072; doi: https://doi.org/10.1101/2024.10.10.24315072
Clausen BE, Amon L, Backer RA, Berod L, Bopp T, Brand A, Burgdorf S, Chen L, Da M, Distler U, Dress RJ, Dudziak D, Dutertre CA, Eich C, Gabele A, Geiger M, Ginhoux F, Giusiano L, Godoy GJ, Hamouda AEI, Hatscher L, Heger L, Heidkamp GF, Hernandez LC, Jacobi L, Kaszubowski T, Kong WT, Lehmann CHK, Lopez-Lopez T, Mahnke K, Nitsche D, Renkawitz J, Reza RA, Saez PJ, Schlautmann L, Schmitt MT, Seichter A, Sielaff M, Sparwasser T, Stoitzner P, Tchitashvili G, Tenzer S, Tochoedo NR, Vurnek D, Zink F, Hieronymus T. 2022. Guidelines for mouse and human DC functional assays. Eur J Immunol n/a. https://doi.org/10.1002/eji.202249925
Dorner H, Stolzer I, Mattner J, Kaminski S, Leistl S, Edrich LM, Schwendner R, Hobauer J, Sebald A, Leikam S, Acera MG, Düll M, Lang R, Seidel G, Seitz T, Hellerbrand C, Fuhrmann G, Distler U, Tenzer S, Eichhorn P, Vieth M, Schramm C, Arnold P, Becker C, Weidinger C, Siegmund B, Atreya R, Leppkes M, Naschberger E, Sampaziotis F, Dietrich P, Rauh M, Wirtz S, Kremer AE, Neurath MF, Günther C. Gut Pathobiont-Derived Outer Membrane Vesicles Drive Liver Inflammation and Fibrosis in PSC-IBD.Gastroenterology. 2024 Jul 9:S0016-5085(24)05203-X. doi: 10.1053/j.gastro.2024.06.032.
Delacher M.*, Schmidleithner L.*, Simon M.*, Stüve P.*, …, Beckhove P., Hehlgans T., Junger H., Geissler E.K., Prantl L., Werner J.M., Schmidl C., Brors B., Imbusch C.D., and Feuerer M. (2024). The effector program of human CD8 T cells supports tissue remodeling. J Exp Med 221 (2): e20230488. doi: 10.1084/jem.20230488 *equal contribution
Elsner F, Hoffmann M, Fahrioglu-Yamaci R, Czyz Z, Feliciello G, Mederer T, Polzer B, Treitschke S, Rümmele P, Weber F, Wiesinger H, Robold T, Sziklavari Z, Sienel W, Hofmann HS, Klein CA. Disseminated cancer cells detected by immunocytology in lymph nodes of NSCLC patients are highly prognostic and undergo parallel molecular evolution. J Pathol. 2022 Nov;258(3):250-263. doi: 10.1002/path.5996. Epub 2022 Sep 23. PMID: 36148685
Faas M, Ipseiz N, Ackermann J, Culemann S, Grüneboom A, Schröder F, Rothe T, Scholtysek C, Eberhardt M, Böttcher M, Kirchner P, Stoll C, Ekici A, Fuchs M, Kunz M, Weigmann B, Wirtz S, Lang R, Hofmann J, Vera J, Voehringer D, Michelucci A, Mougiakakos D, Uderhardt S, Schett G, and Krönke G (2021). IL-33-induced metabolic reprogramming controls the differentiation of alternativ.ely activated macrophages and the resolution of inflammation. Immunity 54: 2531-2546.e2535. doi: 10.1016/j.immuni.2021.09.010
Fang Q, Stehr AM, Naschberger E, Knopf J, Herrmann M and Stürzl M (2022) No NETs no TIME: Crosstalk between neutrophil extracellular traps and the tumor immune microenvironment. Front. Immunol. 13:1075260. doi: 10.3389/fimmu.2022.1075260
Fritz, V., Malek, L., Gaza, A., Wormser, L., Appel, M., Kremer, A. E., Thasler, W. E., Siebler, J., Neurath, M. F., Hellerbrand, C., Bosserhoff, A. K., & Dietrich, P. (2021). Combined De-Repression of Chemoresistance Associated Mitogen-Activated Protein Kinase 14 and Activating Transcription Factor 2 by Loss of microRNA-622 in Hepatocellular Carcinoma. Cancers, 13(5), 1183. https://doi.org/10.3390/cancers13051183
Fuchs, K, Armstark, I, van Roey, R, Hajjaj, Y, D’Avanzo, E, Liguori, R, Ferrazzi, F, Ackermann, J, Amon, L, Alfredo, M, Faas, M, Hübner, J, Hoffmann, M H, Krönke, G, Becker, C, Dudziak, D, Nimmerjahn, F, Brabletz, S, Stemmler, M P, Brabletz, T*, Schuhwerk, H*. (2024). Macrophages foster adaptive anti-tumor immunity by ZEB1-dependent cytotoxic T cell chemoattraction. Pre-print bioRxiv: https://doi.org/10.1101/2024.02.26.582102 , *shared senior author.
Gaculenko, A., Gregoric, G., Popp, V., Seyler, L., Ringer, M., Kachler, K., Wu, Z., Kisel, W., Hofbauer, C., Hofbauer, L. C., Uder, M., Schett, G., Bäuerle, T., & Bozec, A. (2021). Systemic PPARγ Antagonism Reduces Metastatic Tumor Progression in Adipocyte-Rich Bone in Excess Weight Male Rodents. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 36(12), 2440–2452. https://doi.org/10.1002/jbmr.4422
Gamez-Belmonte, R., Mahapatro, M., Erkert, L., Gonzalez-Acera, M., Naschberger, E., Yu, Y., Tena-Garitaonaindia, M., Patankar, J. V., Wagner, Y., Podstawa, E., Schödel, L., Bubeck, M., Neurath, M. F., Stürzl, M., & Becker, C. (2022). Epithelial presenilin-1 drives colorectal tumour growth by controlling EGFR-COX2 signalling. Gut, gutjnl-2022-327323. Advance online publication. https://doi.org/10.1136/gutjnl-2022-327323
Gaza, A., Fritz, V., Malek, L., Wormser, L., Treiber, N., Danner, J., Kremer, A. E., Thasler, W. E., Siebler, J., Meister, G., Neurath, M. F., Hellerbrand, C., Bosserhoff, A. K., & Dietrich, P. (2021). Identification of novel targets of miR-622 in hepatocellular carcinoma reveals common regulation of cooperating genes and outlines the oncogenic role of zinc finger CCHC-type containing 11. Neoplasia (New York, N.Y.), 23(5), 502–514. https://doi.org/10.1016/j.neo.2021.04.001
Georg, P., Grasedyck, L., Klever, M., Schill, R., Spang, R., Wettig T.. Low-rank tensor methods for Markov chains with applications to tumor progression models. J. Math. Biol. 86, 7 (2023). https://doi.org/10.1007/s00285-022-01846-9
Gregoric, G., Gaculenko, A., Nagel, L., Popp, V., Maschauer, S., Prante, O., Saake, M., Schett, G., Uder, M., Ellmann, S., Bozec, A., & Bäuerle, T. (2022). Non-Invasive Characterization of Experimental Bone Metastasis in Obesity Using Multiparametric MRI and PET/CT. Cancers, 14(10), 2482. https://doi.org/10.3390/cancers14102482
Günther C, Winner B, Neurath MF, Stappenbeck TS. Organoids in gastrointestinal diseases: from experimental models to clinical translation. Gut. 2022 Sep;71(9):1892-1908. doi: 10.1136/gutjnl-2021-326560
Guetter S, Koenig C, Koerkel-Qu H, Markiewicz A, Scheitler S, Katzer M, Berneburg M, Renner P, Cucuruz B, Guttenberger L, Naimer V, Weidele K, Treitschke S, Werno C, Jaser H, Bargmann T, Braun A, Weber F, Rachel R, Baumann F, Schmidleithner L, Schambeck K, Mohammadi P, Ulmer A, Haferkamp S, Klein C A, and Werner-Klein M. (2024). Metastasis founder cells activate immunosuppression early in human melanoma metastatic colonization. bioRxiv: 2024.2005.2008.591627. doi: 10.1101/2024.05.08.591627
Heger L, Dudziak D, AmonL, Hatscher L, Kaszubowski T, Lehmann CHK. 2022. Guidelines for DC preparation and flow cytometric analysis of human lymphohematopoietic tissues. Eur J Immunol n/a: e2249917. https://doi.org/10.1002/eji.202249917
Heger L, Hatscher L, Liang C, Lehmann CHK, Amon L, Luhr JJ, Kaszubowski T, Nzirorera R, Schaft N, Dorrie J, Irrgang P, Tenbusch M, Kunz M, Socher E, Autenrieth SE, Purbojo A, Sirbu H, Hartmann A, Alexiou C, Cesnjevar R, Dudziak D. 2023. XCR1 expression distinguishes human conventional dendritic cell type 1 with full effector functions from their immediate precursors. Proc Natl Acad Sci U S A 120: e2300343120. https://doi.org/10.1073/pnas.2300343120
Heinen, H., Seyler, L., Popp, V., Hellwig, K., Bozec, A., Uder, M., Ellmann, S., & Bäuerle, T. (2021). Morphological, functional, and molecular assessment of breast cancer bone metastases by experimental ultrasound techniques compared with magnetic resonance imaging and histological analysis. Bone, 144, 115821. https://doi.org/10.1016/j.bone.2020.115821
Heinlein, Lukas, Benz, Michaela, Kuritcyn, Petr, Bruns, Volker, Hartmann, Arndt, Keil, Felix, Geppert, Carol, Evert, Katja and Wittenberg, Thomas. "Lymph node metastases detection in Whole Slide Images using prototypical patterns and transformer-guided multiple instance learning" Current Directions in Biomedical Engineering, vol. 9, no. 1, 2023, pp. 166-169. https://doi.org/10.1515/cdbme-2023-1042
Hellwig, K., Ellmann, S., Eckstein, M., Wiesmueller, M., Rutzner, S., Semrau, S., Frey, B., Gaipl, U. S., Gostian, A. O., Hartmann, A., Iro, H., Fietkau, R., Uder, M., Hecht, M., & Bäuerle, T. (2021). Predictive Value of Multiparametric MRI for Response to Single-Cycle Induction Chemo-Immunotherapy in Locally Advanced Head and Neck Squamous Cell Carcinoma. Frontiers in oncology, 11, 734872. https://doi.org/10.3389/fonc.2021.734872
Huang J, Demmler R, Mohamed Abdou M, ..., Naschberger E. EXPRESS: Rapid qPCR-Based Quantitative Immune Cell Phenotyping in Mouse Tissues. Journal of Investigative Medicine. 2023;0(ja). doi:10.1177/10815589231210497
Huebner, K., Erlenbach-Wuensch, K., Prochazka, J., Sheraj, I., Hampel, C., Mrazkova, B., Michalcikova, T., Tureckova, J., Iatsiuk, V., Weissmann, A., Ferrazzi, F., Kunze, P., Nalli, E., Sammer, E., Gehring, A., Cheema, M. M., Eckstein, M., Paap, E. M., Soederberg, A., Fischer, C., … Schneider-Stock, R. (2022). ATF2 loss promotes tumor invasion in colorectal cancer cells via upregulation of cancer driver TROP2. Cellular and molecular life sciences : CMLS, 79(8), 423. https://doi.org/10.1007/s00018-022-04445-5
Hübner, J., & Nimmerjahn, F. (2022). Zooming in on dendritic cells for CD40 agonists. Nature cancer, 3(3), 268–269. https://doi.org/10.1038/s43018-022-00340-x
Huttner M, Simeth J, Liguori R, Ferrazzi F and Spang R. (2024). dabih -- encrypted data storage and sharing platform. arXiv 2401.08333. https://doi.org/10.48550/arxiv.2401.08333
Jacobsen A, Siebler J, Grützmann R, Stürzl M, Naschberger E. Blood Vessel-Targeted Therapy in Colorectal Cancer: Current Strategies and Future Perspectives. Cancers (Basel). 2024 Feb 22;16(5):890. doi: 10.3390/cancers16050890
Khare P, Chand J, Ptakova A, Liguori R, Ferrazzi F, Bishnoi M, Vlachova V, Zimmermann K. The TRPC5 receptor as pharmacological target for pain and metabolic disease. Pharmacol Ther. 2024 Oct 7:108727. doi: 10.1016/j.pharmthera.2024.108727. Epub ahead of print. PMID: 39384022.
Krug, J., Rodrian, G., Petter, K., Yang, H., Khoziainova, S., Guo, W., Bénard, A., Merkel, S., Gellert, S., Maschauer, S., Spermann, M., Waldner, M., Bailey, P., Pilarsky, C., Liebl, A., Tripal, P., Christoph, J., Naschberger, E., Croner, R., Schellerer, V. S., … Britzen-Laurent, N. (2022). N-glycosylation regulates intrinsic IFN-γ resistance in colorectal cancer: implications for immunotherapy. Gastroenterology, S0016-5085(22)01294-X. Advance online publication. https://doi.org/10.1053/j.gastro.2022.11.018
Lasierra Losada, M., Pauler, M., Vandamme, N., Goossens, S., Berx, G., Leppkes, M., Schuhwerk, H., Brabletz, S., Brabletz, T., & Stemmler, M. P. (2021). Pancreas morphogenesis and homeostasis depends on tightly regulated Zeb1 levels in epithelial cells. Cell death discovery, 7(1), 138. https://doi.org/10.1038/s41420-021-00522-z
Leone, M., Cazorla-Vázquez, S., Ferrazzi, F., Wiederstein, J. L., Gründl, M., Weinstock, G., Vergarajauregui, S., Eckstein, M., Krüger, M., Gaubatz, S., & Engel, F. B. (2021). IQGAP3, a YAP Target, Is Required for Proper Cell-Cycle Progression and Genome Stability. Molecular cancer research : MCR, 19(10), 1712–1726. https://doi.org/10.1158/1541-7786.MCR-20-0639
Mass, E., Nimmerjahn, F., Kierdorf, K. et al. Tissue-specific macrophages: how they develop and choreograph tissue biology. Nat Rev Immunol 23, 563–579 (2023). https://doi.org/10.1038/s41577-023-00848-y
Mederer T, Elsner F, Robold T, Großer C, Neu R, Ried M, Bleicher S, Schamberger T, Blochberger I, Hofmann HS, Klein CA. EpCAM-positive disseminated cancer cells in bone marrow impact on survival of early-stage NSCLC patients. Lung Cancer. 2022 May;167:73-77. doi: 10.1016/j.lungcan.2022.02.008. Epub 2022 Feb 24. PMID: 35421717 Free article.
MATERIALS AND METHODS: We prospectively collected BM aspirates from 104 non-metastasized NSCLC patients that underwent potentially curative tumor resection from 2011 to 2016 at the Department of Thoracic Surgery of the University Hospital and Hospital Barmherzige Bruder in Reg …
Menche, C., Schuhwerk, H., Armstark, I., Gupta, P., Fuchs, K., van Roey, R., Mosa, M., Hartebrodt, A., Hajjaj, Y., Ezquerra, A. C., Selvaraju, M., Geppert, C., Bärthel, S., Saur, D., Greten, F., Brabletz, S., Blumenthal, D., Weigert, A., Brabletz, T., Farin, H., and Stemmler, M.. ZEB1-mediated fibroblast polarization controls inflammation and sensitivity to immunotherapy in colorectal cancer. EMBO Rep. 2024 Jun 27. doi: 10.1038/s44319-024-00186-7
Menck K, Heinrichs S, Wlochowitz D, Sitte M, Noeding H, Janshoff A, Treiber H, Ruhwedel T, Schatlo B, von der Brelie C, Wiemann S, Pukrop T, Beißbarth T, Binder C, and Bleckmann A. (2021). WNT11/ROR2 signaling is associated with tumor invasion and poor survival in breast cancer. Journal of Experimental & Clinical Cancer Research 40. doi: 10.1186/s13046-021-02187-z
Menck K, Wlochowitz D, Wachter A, Conradi L-C, Wolff A, Scheel A, Korf U, Wiemann S, Schildhaus H-U, Bohnenberger H, Wingender E, Pukrop T, Homayounfar K, Beißbarth T, and Bleckmann A. (2022). High-Throughput Profiling of Colorectal Cancer Liver Metastases Reveals Intra- and Inter-Patient Heterogeneity in the EGFR and WNT Pathways Associated with Clinical Outcome. Cancers 14. doi: 10.3390/cancers14092084
Naschberger E, Flierl C, Huang J, Erkert L, Gamez-Belmonte R, Gonzalez-Acera M, Bober M, Mehnert M, Becker C, Schellerer VS, Britzen-Laurent N and Stürzl M (2023), Analysis of the interferon-γ-induced secretome of intestinal endothelial cells: putative impact on epithelial barrier dysfunction in IBD. Front. Cell Dev. Biol. 11:1213383. doi: 10.3389/fcell.2023.1213383
Naschberger E, Fuchs M, Dickel N, Kunz M, Popp B, Anchang CG, Demmler R, Lyu Y, Uebe S, Ekici AB, Geppert CI, Hartmann A, Flierl C, Petter K, Gass T, Völkl S, Scharl M, Ramming A, Günther C, Merkel S, Schellerer VS, Stürzl M. Tumor microenvironment-dependent epigenetic imprinting in the vasculature predicts colon cancer outcome. Cancer Commun. http://doi.org/10.1002/cac2.12489
Nimmerjahn, F., & Ravetch, J. V. (2021). Four keys to unlock IgG. The Journal of experimental medicine, 218(3), e20201753. https://doi.org/10.1084/jem.20201753
Nimmerjahn, F., Vidarsson, G. & Cragg, M.S. Effect of posttranslational modifications and subclass on IgG activity: from immunity to immunotherapy. Nat Immunol 24, 1244–1255 (2023). https://doi.org/10.1038/s41590-023-01544-8
Pfahler, S., Georg, P., Schill R., Klever, M., Grasedyck, L., Spang, R., Wettig, T.. Taming numerical imprecision by adapting the KL divergence to negative probabilities, 06 February 2024, 2312.13021 (arxiv.org)
Polisetti, N., Gießl, A., Zenkel, M., Heger, L., Dudziak, D., Naschberger, E., Stich, L., Steinkasserer, A., Kruse, F. E., & Schlötzer-Schrehardt, U. (2021). Melanocytes as emerging key players in niche regulation of limbal epithelial stem cells. The ocular surface, 22, 172–189. https://doi.org/10.1016/j.jtos.2021.08.006
Probst HC, Stoitzner P, Amon L, Backer RA, Brand A, Chen J, Clausen BE, Dieckmann S, Dudziak D, Heger L, Hodapp K, Hornsteiner F, Hovav AH, Jacobi L, Ji X, Kamenjarin N, Lahl K, Lahmar I, Lakus J, Lehmann CHK, Ortner D, Picard M, Roberti MP, Rossnagel L, Saba Y, Schalla C, Schlitzer A, Schraml BU, Schutze K, Seichter A, Sere K, Seretis A, Sopper S, Strandt H, Sykora MM, Theobald H, Tripp CH, Zitvogel L. 2022. Guidelines for DC preparation and flow cytometry analysis of mouse nonlymphoid tissues. Eur J Immunol n/a. https://doi.org/10.1002/eji.202249819
Reitinger, C., Ipsen-Escobedo, A., Hornung, C., Heger, L., Dudziak, D., Lux, A., & Nimmerjahn, F. (2022). Modulation of urelumab glycosylation separates immune stimulatory activity from organ toxicity. Frontiers in immunology, 13, 970290. https://doi.org/10.3389/fimmu.2022.970290
Ruh, M., Stemmler, M. P., Frisch, I., Fuchs, K., van Roey, R., Kleemann, J., Roas, M., Schuhwerk, H., Eccles, R. L., Agaimy, A., Baumhoer, D., Berx, G., Müller, F., Brabletz, T., & Brabletz, S. (2021). The EMT transcription factor ZEB1 blocks osteoblastic differentiation in bone development and osteosarcoma. The Journal of pathology, 254(2), 199–211. https://doi.org/10.1002/path.5659
Rupp, K., Lösch, A., Hu, Y., Nie, C., Schill, R., Klever, M., Pfahler, S., Grasedyck, L., Wettig, T., Beerenwinkel, N., Spang, R.. (2024). Modeling metastatic progression from cross-sectional cancer genomics data. doi: 10.1101/2024.01.30.577989
Rupp, K., Schill, R., Süskind, J., Georg, P., Klever, M., Lösch, A., Grasedyck, L., Wettig, T., Spang, R.. (2024) Differentiated uniformization: a new method for inferring Markov chains on combinatorial state spaces including stochastic epidemic models. Comput Stat (2024). https://doi.org/10.1007/s00180-024-01454-9
Saha A, Gavert N, Brabletz T, Ben-Ze'ev A (2022). Downregulation of the Tumor Suppressor TFF1 Is Required during Induction of Colon Cancer Progression by L1. Cancers (Basel), 14(18):4478. doi: 10.3390/cancers14184478
Schill, R., Klever, M., Lösch, A., Hu, Y. L., Vocht, S., Rupp, K., Grasedyck, L., Spang, R., Beerenwinkel, N.. Overcoming Observation Bias for Cancer Progression Modeling. bioRxiv 2023.12.03.569824; https://doi.org/10.1101/2023.12.03.569824
Schill, R., Klever, M., Rupp, K., Hu, Y.L., Lösch, A., Georg, P., Pfahler, S., Vocht, S., Hansch, S., Wettig, T., Grasedyck, L., Spang, R. (2024). Reconstructing Disease Histories in Huge Discrete State Spaces. Künstl Intell (2024). https://doi.org/10.1007/s13218-023-00822-9
Schlieben LD#, Carta MG#, Moskalev EA, Stöhr R, Metzler M, Besendörfer M, Meidenbauer N, Semrau S, Janka R, Grützmann R, Wiemann S, Hartmann A, Agaimy A, Haller F, Ferrazzi F. Machine Learning-Supported Diagnosis of Small Blue Round Cell Sarcomas Using Targeted RNA Sequencing. J Mol Diagn. 2024 May;26(5):387-398. doi: 10.1016/j.jmoldx.2024.02.002
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